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A Nutritional Approach to Alzheimer's DiseaseNutrients for Memory

The Hawaii Dementia Prevention Trial

Steve Blake, ScD



July, 2017

"It was good meeting you today and I very much appreciated your informative discussion of nutritional approaches to prevention and treatment of Alzheimer's disease and related dementias."
BRENT P. FORESTER, MD Instructor in Psychiatry, Harvard. Director Mood Disorders Division, Geriatric Psychiatry Research Program and Site Director, McLean Hospital,
Harvard Medical School.

      $9.95 to download the entire 183 page PDF book. Click below:


      Please see below for the table of contents and the scientific references.

      Read a two-page article on nutrition and Alzheimer's disease

      Table of Contents

      Introduction       2
      Table of Contents            4
      Table of figures 11
      Chapter 1: Diet can be powerful                13
      Age and delaying dementia         13
      The Nurses’ Health Study             14
      The MIND diet  15
      Rush Memory and Aging Project               16
      Supplements to improve cognition          18
      The Hawaii Dementia Prevention Trial    20
      Chapter 2: Overview of Alzheimer’s disease        24
      Changes to the brain in Alzheimer’s disease        25
      What are amyloid plaques           27
      Meet tau tangles             29
      An epidemic of Alzheimer’s disease        31
      Junk food, diabetes, and Alzheimer’s disease     33
      Diabetes and dementia risk         34
      Drugs and Alzheimer’s disease  34
      Prevalence of dementia               37
      Chapter 3: Food and nutrient changes that worked          40
      Vitamin E             40
      Advanced glycation endproducts              41
      Berries for memory        43
      Vascular dementia and saturated fat      44
      Supplements used in the trial     46
      Two B-vitamins 46
      SAMe    47
      Antioxidants      48
      Vitamin E supplement used        49
      Vitamin C supplement used        50
      Coenzyme Q10 51
      Four antioxidant minerals            52
      Two medical plants used              53
      Ginkgo biloba    54
      Centella asiatica (gotu kola)         54
      Chapter 4: Folate, vitamin B12, homocysteine, and SAMe             56
      How amyloid plaques are made                56
      How two B-vitamins reduce the formation of amyloid plaques   59
      Folate and vitamin B12 transform homocysteine into SAMe.       61
      Homocysteine and Alzheimer’s disease 62
      Are we getting enough Folate and Vitamin B12?                65
      Getting enough vitamin B12        66
      SAMe and Alzheimer’s disease  69
      Chapter 5: Advanced Glycation Endproducts       72
      Absorption of AGEs        73
      Formation of AGEs          74
      AGEs as a cause of brain damage in Alzheimer’s disease                79
      Cooking methods to reduce AGEs in food             81
      Chapter 6: Antioxidants and Alzheimer’s disease              83
      Vitamins E and C protect brain cell membranes from free radical attack  84
      Causes of excess free radicals    85
      Radiation and medical testing as sources of free radicals                86
      Plant Antioxidants Defend Us from Free Radicals              88
      Vitamin E and Alzheimer’s disease           88
      Why synthetic vitamin E is ineffective     90
      Food sources of vitamin E            95
      Vitamin C and Alzheimer’s disease           97
      Dietary sources of antioxidants 99
      Plant antioxidants            102
      Antioxidants made in your body               106
      Protecting our little energy factories, the mitochondria  109
      Coconut oil, ketones, and mitochondrial function             110
      Coenzyme Q10, the only fat-soluble antioxidant made in the body           113
      Are statins related to memory loss?        115
      Antioxidant content in diets        119
      Chapter 7: Saturated fat and dementia  121
      Saturated fat in diets      123
      Blood cholesterol and risk of Alzheimer’s disease             126
      Oxidized dietary cholesterol and vascular dementia         128
      Crystallized cholesterol 133
      Lowering cholesterol using phytosterols               135
      Fiber and blood cholesterol         138
      Chapter 8: Medical plants to treat Alzheimer’s disease   140
      Ginkgo biloba    140
      How does ginkgo work?                141
      How ginkgo protects brain cells 142
      Ginkgo and bleeding      143
      Ginkgo and memory       144
      Gotu kola            145
      Gotu kola as an antioxidant         146
      Gotu kola improves memory scores        146
      Gotu kola for memory in healthy elders                147
      Chapter 9: Exercise and Alzheimer’s disease       149
      Exercise and vascular dementia 150
      Muscle strength and Alzheimer’s disease             150
      Exercise decreases brain shrinkage          151
      Exercise can reduce risk of dementia      152
      Exercise can cut risk of dementia in half 152
      More exercise cuts risk further  153
      Chapter 11: Environmental toxins and Alzheimer’s disease           155
      Seafood, mercury, and DHA        155
      Organophosphate pesticides and dementia        158
      Organochlorines and dioxins       159
      Aluminum, does it cause Alzheimer’s disease?   160
      Chapter 10: Nutritional approaches to Alzheimer’s disease           162
      Acknowledgements       166
      Index    167
      Reference citations         172

      Table of figures
      Figure 1  Three supplements helped cognition   19
      Figure 2  Improvement in our trial            21
      Figure 3  No degeneration was noted with food changes               22
      Figure 4  Normal decline of memory score            22
      Figure 5  Normal brains on the left and advanced Alzheimer’s disease on the right            25
      Figure 6  Amyloid plaques look like fuzz balls between neurons.                27
      Figure 7   Amyloid plaques and tau tangles           28
      Figure 8  Tangled neuron looks like a fried egg    29
      Figure 9  The great increase in Alzheimer's death rate     31
      Figure 10 Dementia forecast for less developed countries            37
      Figure 11 Forecast increase in Alzheimer's disease            38
      Figure 12 Types of dementia graph          45
      Figure 13 Folate and vitamin B12 and amyloid plaque      57
      Figure 14 How amyloid plaque is formed               58
      Figure 15 Homocysteine and B-vitamins                60
      Figure 16 Folate can be low on an American diet                64
      Figure 17 Folate in food from the Diet Doctor      66
      Figure 18 Folate and vitamin B12 in diets               68
      Figure 19 List of foods highest in AGEs    77
      Figure 20 Synthetic vitamin E structure   92
      Figure 21 Nut and seed sources of vitamin E        96
      Figure 22 Vitamin E in some common foods         97
      Figure 23 Vitamin C in food graph             100
      Figure 24 Antioxidants in common diets                101
      Figure 25 A tiny amount of manganese on an Atkin's diet              108
      Figure 26 Cognitive performance among the elderly in relation to the intake of plant foods. The Hordaland Health Study.                120
      Figure 27 Saturated fat in various food servings 123
      Figure 28 A mostly clogged artery             125
      Figure 29 LDL diagram showing signaling proteins              131
      Figure 30 Cholesterol crystals in plaque  135
      Figure 31 Sources of plant sterols to block cholesterol     137

      Reference Citations:

      Dietary intakes of berries and flavonoids in relation to cognitive decline, Devore, Elizabeth E., et al. Annals of neurology 72.1 (2012): 135-143.
      MIND diet associated with reduced incidence of Alzheimer's disease, Morris, Martha Clare, et al. Alzheimer's & Dementia 11.9 (2015): 1007-1014.
      Nutrition and risk of dementia: overview and methodological issues, Morris, Martha Clare, Annals of the New York Academy of Sciences 1367.1 (2016): 31-37.
      Fruit and vegetable consumption and cognitive decline in aging women, Kang et al., Annals of Neurology 57.5 (2005): 713-720.
      Effects of vitamins E and C combined with β‑carotene on cognitive function in the elderly, Li, Yonghua, et al. Experimental and therapeutic medicine 9.4 (2015): 1489-1493.
      Proteolytically Inactive Insulin-Degrading Enzyme Inhibits Amyloid Formation Yielding Non-Neurotoxic Ab Peptide Aggregates, Tullio et al., PLoS ONE, April 2013, Volume 8, Issue 4, e59113.
      Insulin Resistance and Alzheimer´s Disease: Molecular Links & Clinical Implications, Neumann et al., Current Alzheimer Research, 2008, Vol. 5, No. 5.
      Alzheimer’s beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme, Kurochkin et al., Federation of European Biochemical Societies Letters 345 (1994) 33-37.
      Midlife cardiovascular risk factors and risk of dementia in late life, Whitmer, Rachel A., et al. Neurology 64.2 (2005): 277-281.
      Diabetes, Alzheimer disease, and vascular dementia A population-based neuropathologic study, Ahtiluoto, S., et al. Neurology 75.13 (2010): 1195-1202.
      Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer Disease, Clarke, et al.
      Archives of Neurology, November 1998, volume 55.
      Homocysteine, folate, and vitamin B-12 on mild cognitive impairment, Alzheimer Disease, and vascular dementia, Quadri, et al. American Journal of Clinical Nutrition, Vol. 80, No. 1, 114-122, July 2004.
      Homocysteine and folate as risk factors for dementia and Alzheimer Disease, Ravaglia, et al.
      American Journal of Clinical Nutrition, Vol. 82, No. 3, 636-643, September 2005.
      Protein Phosphatase 2A Methyltransferase Links Homocysteine Metabolism with Tau and Amyloid Precursor Protein Regulation, Sontag et al. The Journal of Neuroscience, March 14, 2007, 27(11):2751–2759.
      S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production, Fuso et al. Molecular and Cellular Neuroscience 28 (2005) 195– 204.
      Protein Phosphatase 2A Methyltransferase Links Homocysteine Metabolism with Tau and Amyloid Precursor Protein Regulation, Sontag et al. The Journal of Neuroscience, March 14, 2007, 27(11):2751–2759.
      S -Adenosylmethionine Is Decreased in the Cerebrospinal Fluid of Patients with Alzheimer’s Di sease. Linnebank et al. Neurodegenerative Dis 2010;7:373–378.
      S-Adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: A double-blind cross-over trial. Najm et al. BMC Musculoskeletal Disorders 2004, 5.
      Does Accumulation of Advanced Glycation End Products Contribute to the Aging Phenotype? Semba et al. J Gerontol A Biol Sci Med Sci. 2010 September;65A(9):963–975.
      Orally absorbed reactive glycation products (glycotoxins): An environmental risk factor in diabetic nephropathy, Koschinsky et al. Proc. Natl. Acad. Sci. USA 94 (1997).
      Active glycation in neurofibrillary pathology of Alzheimer disease: N-(Carboxymethyl) lysine and hexitol-lysine, Castellani et al. Free Radical Biology and Medicine Volume 31, Issue 2, 15 July 2001, Pages 175-180.
      Advanced Glycosylation End Products and Nutrition—A Possible Relation with Diabetic Atherosclerosis and How to Prevent It, Xanthis, Vol. 72, Nr. 8, 2007, Journal of Food Science.
      Dietary Advanced Glycation End Products and Aging, Luevano-Contreras et al. Nutrients 2010, 2, 1247-1265.
      Active glycation in neurofibrillary pathology of Alzheimer disease: N-(Carboxymethyl) lysine and hexitol-lysine, Castellani et al. Free Radical Biology and Medicine Volume 31, Issue 2, 15 July 2001, Pages 175-180.
      Amplifiers of Systemic Inflammation– The Role Advanced Glycation and Lipoxidation End Products in Foods,
      Stig Bengmark, Kuwait Medical Journal 2008, 40 (1): 3-17.
      Age- and Stage-dependent Accumulation of Advanced Glycation End Products in Intracellular Deposits in Normal and Alzheimer’s Disease Brains, Luth 2005 Cerebral Cortex February 2005;15:211—220.
      Advanced Glycosylation End Products and Nutrition—A Possible Relation with Diabetic Atherosclerosis and How to Prevent It, Xanthis, Vol. 72, Nr. 8, 2007, Journal of Food Science.
      Gofman, J. W. and E. O’Conner. X-Rays: Health Effects of Common Exams. San Francisco: Sierra Club Books, 1985.
      A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer’s disease, Sano et al. April 24, 1997, JAMA Volume 336 Number 17.
      Molecular bases of the treatment of Alzheimer’s disease with antioxidants: prevention of oxidative stress, Jose Vina, et al. Molecular Aspects of Medicine 25 (2004) 117–123.
      Dietary Intake of Antioxidant Nutrients and the Risk of Incident Alzheimer Disease in a Biracial Community Study, Morris et Al. JAMA, June 26, 2002—Vol 287, No. 24.
      High plasma levels of vitamin E forms and reduced Alzheimer’s disease risk in advanced age, Journal of Alzheimer’s Disease, volume 20, #4 2010.
      Vitamins and Minerals Demystified, Blake, McGraw-Hill, 2008.
      Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change, Morris et al. Am J Clin Nutr 2005;81:508 –14.
      Vitamin E Forms in Alzheimer's Disease: A Review of Controversial and Clinical Experiences, Usoro and Mousaa, Critical Reviews in Food Science and Nutrition Volume 50, Issue 5, 2010, Pages 414 – 419.
      Lowered plasma vitamin C, but not vitamin E, concentrations in dementia patients. Charlton et al. The Journal of Nutrition Health & aging, 2004, vol. 8, no2, pp. 99-107.
      Vitamin E and vitamin C supplement use and risk of incident Alzheimer’s disease, Morris et al. Alzheimer Disease & Associated Disorders: September 1998 - Volume 12 - Issue 3.
      Association of vitamin E and C supplement use with cognitive function and dementia in elderly men. Masaki et al. Neurology 2000;54:1265-1272.
      Dietary Intake of Antioxidants and Risk of Alzheimer Disease, Engelhart et al. JAMA. 2002;287:3223-3229.
      The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide, Carlsen et al. Nutrition Journal 2010, 9:3.
      Grape juice, berries, and walnuts affect brain aging and behavior, Joseph et al. Journal of Nutrition 139: 1813S-1817S 2009.
      Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment, Krikorian et al. British Journal of Nutrition (2010), 103, 730–734.
      Nutritional status of selenium in Alzheimer's disease patients, Cardoso et al. British Journal of Nutrition (2010), 103: 803-806 .
      Coenzyme Q10 Attenuates β-Amyloid Pathology in the Aged Transgenic Mice with Alzheimer Presenilin 1 Mutation, Yang et al. J Mol Neurosci (2008) 34:165–171.
      Review: Fosslien, “Mitochondrial Medicine – Molecular Pathology of Defective Oxidative Phosphorylation,” Annals of Clinical & Laboratory Science, vol. 31, no. 1, 2001.
      Catarina et al., “Coenzyme Q and Mitochondrial Disease,” Dev Disabil Res Rev. 2010 June ; 16(2): 183–188. doi:10.1002/ddrr.108.
      Review: Fosslien, “Mitochondrial Medicine – Molecular Pathology of Defective Oxidative Phosphorylation,” Annals of Clinical & Laboratory Science, vol. 31, no. 1, 2001.
      Rojas-Fernandez and Cameron, “Is Statin-Associated Cognitive Impairment Clinically Relevant? A Narrative Review and Clinical Recommendations,” Ann Pharmacother 2012;46:549-57.
      Hyttinen et al., “Long-Term Statin Therapy is Associated with Better Episodic Memory in Aged Familial Hypercholesterolemia Patients in Comparison with Population Controls,” Journal of Alzheimer’s Disease 21 (2010) 611–617.
      Dolga et a., “Statins — increasing or reducing the risk of Parkinson's disease?,” Experimental Neurology 228 (2011) 1–4.
      Shintani et al., “Obesity and cardiovascular risk intervention through the ad libitum feeding of traditional Hawaiian diet,” Am J Clin Nutr 1991:53:1647S-51S.
      Cognitive performance among the elderly in relation to the intake of plant foods. The Hordaland Health Study, Eha Nurk, British Journal of Nutrition (2010), 104, 1190–1201.
      Nonoptimal Lipids Commonly Present in Young Adults and Coronary Calcium Later in Life: The CARDIA (Coronary Artery Risk Development in Young Adults), Pletcher et al. Annals of Internal Medicine, August 3, 2010, vol. 153 no. 3 137-146.
      Mechanisms by which Dietary Fatty Acids Modulate Plasma Lipids, Fernandez and West, J. Nutr. 135:2075-2078, September 2005.
      Food Combination and Alzheimer Disease Risk, A Protective Diet, Yian Gu et al. Arch Neurol. 2010;67(6).
      Dietary Fats and the Risk of Incident Alzheimer Disease, Morris et al. Archives of Neurology 2003; 60: 194-200.
      Apolipoprotein E4 Allele, Elevated Midlife Total Cholesterol Level, and High Midlife Systolic Blood Pressure Are Independent Risk Factors for Late-Life Alzheimer Disease, Kivipelto et al. Annals of Internal Medicine 2002, vol. 137, no3, pp. 149-155.
      Association of Higher Levels of High-Density Lipoprotein Cholesterol in Elderly Individuals and Lower Risk of Late-Onset Alzheimer Disease, Reitz et al. Archives of Neurology. 2010;67(12):1491-1497.
      Independent inhibition of Alzheimer’s disease B- and G-Secretase cleavage by lowered cholesterol levels, Grimm et al. The Journal of Biological Chemistry Vol. 283, No. 17, pp. 11302–11311, April 25, 2008.
      Oxysterols: A world to explore, Otaegui-Arrazola et al., Food and Chemical Toxicology 48 (2010) 3289–3303.
      Oxidized Cholesterol in the Diet Accelerates the Development of Aortic Atherosclerosis, Staprans et al., Arteriosclerosis, Thrombosis, and Vascular Biology. 1998;18:977-983.
      Cholesterol crystals piercing the arterial plaque and intima trigger local and systemic inflammation, Abela, Journal of Clinical Lipidology (2010) 4, 156–164.
      Continuous Dose-Response Relationship of the LDL-Cholesterol–Lowering Effect of  Phytosterol Intake. Demonty et al. Journal of Nutrition 139: 271–284, 2009.
      The effects of phytosterols present in natural food matrices on cholesterol metabolism and LDL-cholesterol: a controlled feeding trial, Lin et al., European Journal of Clinical Nutrition (2010) 64, 1481–1487.
      Plant sterol consumption frequency affects plasma lipid levels and cholesterol kinetics in humans, AbuMweis et al., European Journal of Clinical Nutrition (2009) 63, 747–755.
      Phytosterol Composition of Nuts and Seeds Commonly Consumed in the United States, Phillips et al., J. Agric. Food Chem., 2005, 53 (24), pp 9436–9445.
      Ginkgo biloba for dementia: a systematic review of double-blind placebo-controlled trials, Ernst E, Pittler, Clinical Drug Investigation.1999;17:301-8.
      Flavonoids as modulators of memory and learning: molecular interactions resulting in behavioural effects, Rendeiro et al. Proceedings of the Nutrition Society 71.2 (2012): 246-262.
      Radioprotection by plant products: present status and future prospects, Arora et al. Phytotherapy Research 19.1 (2005): 1-22.
      The neuroprotective potential of flavonoids: a multiplicity of effects, Vauzour et al. Genes & nutrition 3.3-4 (2008): 115-126.
      The ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by β‐amyloid, Bastianetto et al. European Journal of Neuroscience 12.6 (2000): 1882-1890.
      Ginkgo biloba, Sierpina et al. Am Fam Physician, 2003 Sept 1 68(5) 923-926.
      Ginkgo  biloba and Donepezil: a comparison in the treatment of Alzheimer’s dementia in a randomized placebo-controlled double-blind study, Mazza et al. European Journal of Neurology 2006, 13: 981–985.
      Effects of Gingko biloba supplementation in Alzheimer's disease patients receiving cholinesterase inhibitors: data from the ICTUS study, Canevelli et al. Phytomedicine 21.6 (2014): 888-892.
      Centella asiatica Extract Selectively Decreases Amyloid β Levels in Hippocampus of Alzheimer’s Disease Animal Model, Dhanasekaran et al. Phytotherapy Research. 23, 14–19 (2009).
      Effect of different extracts of Centella asiatica on cognition and markers of oxidative stress in rats,
      Kumar and Gupta, Journal of Ethnopharmacology, Volume 79, Issue 2, February 2002, Pages 253-260.
      Comparison on Cognitive Effects of Centella Asiatica in Healthy Middle Age Female and Male Volunteers, Dev et al. European Journal of Scientific Research Vol.31 No.4 (2009), pp.553-565.
      Effect of centella asiatica on mild cognitive impairment (MCI) and other common age-related clinical problems, Tiwari et al. Digest Journal of Nanomaterials and Biostructures Vol. 3, No.4, December 2008, p. 215 – 220.
      Exercise Plus Behavioral Management in Patients With Alzheimer Disease: A Randomized Controlled Trial,
      Teri et al. JAMA. 2003;290(15):2015-2022.
      Physical Activity, Diet, and Risk of Alzheimer Disease, Scarmeas et al. JAMA, August 12, 2009—Vol 302, No. 6.
      Effects of Aerobic Exercise on Mild Cognitive Impairment, A Controlled Trial, Laura D. Baker et al. Arch Neurol. 2010;67(1):71-79.
      Association of muscle strength with the risk of Alzheimer disease and the rate of cognitive decline in community-dwelling older persons, Boyle, et al. (2009) Arch Neurol 66, 1339-1344.
      Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease, Smith et al."Frontiers in Aging Neuroscience 6 (2014).
      Physical activity, diet, and risk of Alzheimer disease. Scarmeas et al., (2009) JAMA 302, 627-637.
      Alzheimer’s disease – the ways of prevention. Kivipelto and Solomon (2008) J Nutr Health Aging 12, 89S-94S.
      Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Larson et al., (2006) Ann Intern Med 144, 73-81.
      Physical activity and risk of cognitive impairment and dementia in elderly persons. Laurin et al., (2001) Arch Neurol 58, 498-504.
      Physical exercise and mild cognitive impairment: A population-based study, Geda et al. Archives of Neurology, Vol 67 (NO. 1), JAN 2010, 80-86.
      Effect of mercury levels and seafood intake on cognitive function in middle-aged adults, Masley et al., Integrative Medicine 11.3 (2012): 32.
      No Effect of DHA Supplementation in Slowing Alzheimer's Progression, Quinn et al. JAMA. 2010;304:1903-1911, 1952-1953.
      Low level methylmercury exposure affects neuropsychological function in adults, Yokoo et al. Environmental Health 2.1 (2003): 8.
      Neurodegenerative Memory Disorders: A Potential Role of Environmental Toxins, Caban-Holt et al. Neurologic Clinics 23 (2005) 485–521.
      Consumption of organic meat does not diminish the carcinogenic potential associated with the intake of persistent organic pollutants (POPs) Hernández et al. Environmental Science and Pollution Research 24.5 (2017): 4261-4273.
      Organochlorine pesticide levels and risk of Alzheimer’s disease in north Indian population Singh et al. Human & experimental toxicology 32.1 (2013): 24-30.
      Elevated serum pesticide levels and risk for Alzheimer disease Richardson, Jason et al. JAMA neurology 71.3 (2014): 284-290.
      Low aluminum levels in the human brain from controls and Alzheimer patients, Delacourte et al. The Journal of Applied Neuroscience, Vol.2005.1-14.
      Brain aluminum in aging and Alzheimer disease, John R. McDermott et al. Neurology, May 10, 2011, 76 (19).
      Content of Brain Aluminum Is Not Elevated in Alzheimer Disease, Bjertness et al. Alzheimer Disease & Associated Disorders: Fall 1996 - Volume 10 - Issue 3.
      Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology, Sparks et al. The Journal of nutrition, health & aging 2006, vol. 10, no4, pp. 247-254.
      Evidence for Participation of Aluminum in Neurofibrillary Tangle Formation and Growth in Alzheimer’s Disease, Walton, Journal of Alzheimer’s Disease 22 (2010) 65–72.
      Link between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade Hypotheses, Kawahara and Kato-Negish, International Journal of Alzheimer’s Disease. 2011; v2011.
      Aluminum in the Diet and Alzheimer's Disease: From Current Epidemiology to Possible Disease-Modifying Treatment, Frisardi et al. Journal of Alzheimer's Disease, Volume 20, Number 1 / 2010.